Melt In Your Mouth Chicken

Melt in Your Mouth Chicken has just a few simple ingredients and is quick to make! It’s some of the most tender, juicy, and flavorful chicken you’ve ever had!

Plated chicken breast fillet with white cheese sauce and asparagus spears

No boring or bland dish here! The combination of the seasonings, mayonnaise, sour cream, or Greek yogurt and parmesan is a beautiful thing! You’re going to want to sop up every last bite of this amazing sauce-y melt in your mouth chicken! Bonus…who doesn’t like a meal that takes less than 10 minutes to prep?

Save The Recipe!

Add your email below and we’ll send it straight to your inbox+ you’ll receive all our newest recipes!

The chicken absorbs the flavors of the mixture spread on top and becomes incredibly tender. The end product is also versatile in how it can be served. On rice, pasta, in a wrap, or as a salad topper, it’s yummy in every way! It’s a perfect meal any day of the week and great for entertaining.

What You’ll Need

  • Boneless, Skinless Chicken Breasts, Thighs, or Tenders
  • Light or Regular Mayonnaise
  • Light or Regular Plain Greek Yogurt or Sour Cream
  • Parmesan Cheese
  • Seasoning Salt or Salt
  • Black Pepper
  • Garlic Powder
Ingredients for melt in your mouth chicken

Tools You’ll Need

  • 13″x9″ Baking Dish

How to Make Melt in Your Mouth Chicken

  1. First, prepare the chicken. If you have large chicken breasts, you’ll need to halve them horizontally. If using thighs, they will likely be small enough. Distribute the chicken evenly in a baking dish. You can season the chicken with salt or seasoning salt on both sides if you’d like.
  2. For the sauce, in a medium bowl, whisk together mayonnaise, yogurt or sour cream, parmesan cheese, and spices.
whisking sauce ingredients together
  1. Spread the sauce mixture evenly in one layer on top of the chicken.
Spreading the sauce on the chicken
  1. Bake at 375ºF for 35-40 minutes. Broil for 1-2 minutes. Using a meat thermometer, check to ensure the chicken has reached an internal temperature of 165ºF.
Fully cooked melt in your mouth chicken in a baking dish

Tips and Substitutions

  • Any boneless, skinless chicken cut works in this dish. As noted above, if you’re using larger chicken breasts, they will need to be halved for optimal cooking. Most chicken thighs will be sized appropriately. Chicken tenders can also be used in this recipe. It’s most important that the chicken pieces are equal in size to cook evenly. Chicken tenders will likely be cooked through at around 30-35 minutes.
  • If you want to sear the chicken first, that’s perfectly fine! Just decrease the baking time to 25-30 minutes.
  • There are LOTS of ways to serve this delicious chicken!
    • Over Egg Noodles
    • Over White, Brown, or Veggie Rice
    • Over Mashed Potatoes
    • Between Toasted Garlic Bread
    • In a Wrap
    • On Top of a Salad
  • What to serve with Melt In Your Mouth Chicken besides the accompaniments listed above:
  • You can prep this dinner in advance. Just assemble, cover, and refrigerate. When you’re ready to bake it, either set it out at room temperature for 30 minutes prior to baking or add 3-5 minutes to the bake time. Of course, just check the internal temperature to ensure doneness.
two plates of chicken and sauce with asparagus spears

Storage

  • Store in an air-tight container in the refrigerator up to 3 days.
  • Dishes with dairy-based ingredients like these don’t freeze and thaw well due to the separation of the ingredients.

More Recipes Like This

Print Recipe Rate this Recipe Pin Recipe
4.86 from 7 votes

Melt In Your Mouth Chicken

This amazing recipe has just a few simple ingredients and is quick to make! It's some of the most tender, juicy and flavorful chicken you've ever had! 
Prep Time15 minutes
Cook Time45 minutes
Total Time1 hour
Course: Main Course
Cuisine: American
Keyword: chicken
Servings: 8 servings
Calories: 321kcal

Ingredients
 

  • 2-2 1/2 lb boneless, skinless chicken breasts or thighs
  • 1 cup light mayonnaise
  • 1 cup nonfat plain Greek yogurt or sour cream
  • 2 cups shredded parmesan cheese
  • 1/2 tsp seasoning salt
  • 1 tsp black pepper
  • 1 tsp garlic powder

Instructions

  • Preheat the oven to 375ºF. 
  • For the topping, in a medium bowl combine mayonnaise, yogurt or sour cream, parmesan cheese, salt, pepper, and garlic powder. Mix well until smooth. 
  • Halve or Flatten chicken to a ½-inch thickness. Place in a 13"x9" baking dish. Spread the topping on the chicken in an even layer. 
  • Bake 35-40 minutes, then broil on high 1-2 minutes. Ensure an internal temperature of 165°F is reached.

Video

Nutrition

Serving: 5oz | Calories: 321kcal | Carbohydrates: 2.5g | Protein: 35.5g | Fat: 19g
Tried this recipe?Mention @dinnerin321 or tag #dinnerin321!
Laura

About Laura

Taught by some of the best, cooking and entertaining has always been my favorite hobby. Food is my love language! The conception of Dinner in 321 came from my family talks that sharing our dinners would help others learn new skills, tasty recipes, and make cooking fun! Read more…

Similar Posts

6 Comments

  1. 5 stars
    My 17-yo daughter wanted to make this…. OMG, sooooo good. leftovers were just as good. thank you for sharing.

    1. You’re very welcome and thank you for telling me too! That is FANTASTIC!! I’m so excited she made it and it was such a hit!

4.86 from 7 votes (5 ratings without comment)

Leave a Reply

Your email address will not be published. Required fields are marked *

Recipe Rating